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Gamma-interferon inhibits collagen synthesis in vivo in the mouse.

Subcutaneous implantation of osmotic pumps into CAF1 mice resulted in the formation of thick fibrous capsules around the pumps. When pumps were loaded with recombinant murine gamma-interferon (rMuIFN-gamma) to deliver 2 X 10(3) U/h for 14 d, there was a marked decrease in thickness and collagen cont...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Granstein, R D, Murphy, G F, Margolis, R J, Byrne, M H, Amento, E P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424325/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3104404/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112945
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