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Gamma-interferon inhibits collagen synthesis in vivo in the mouse.

Subcutaneous implantation of osmotic pumps into CAF1 mice resulted in the formation of thick fibrous capsules around the pumps. When pumps were loaded with recombinant murine gamma-interferon (rMuIFN-gamma) to deliver 2 X 10(3) U/h for 14 d, there was a marked decrease in thickness and collagen cont...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Granstein, R D, Murphy, G F, Margolis, R J, Byrne, M H, Amento, E P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC424325/
https://ncbi.nlm.nih.gov/pubmed/3104404
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