Gamma-interferon inhibits collagen synthesis in vivo in the mouse.

Subcutaneous implantation of osmotic pumps into CAF1 mice resulted in the formation of thick fibrous capsules around the pumps. When pumps were loaded with recombinant murine gamma-interferon (rMuIFN-gamma) to deliver 2 X 10(3) U/h for 14 d, there was a marked decrease in thickness and collagen cont...

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Pubblicato in:	J Clin Invest
Autori principali:	Granstein, R D, Murphy, G F, Margolis, R J, Byrne, M H, Amento, E P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3104404/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112945
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