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O6 alkylguanine-DNA alkyltransferase activity in human myeloid cells.
The association between alkylating agent exposure and acute nonlymphocytic leukemia in humans indicates that myeloid cells may be particularly susceptible to mutagenic damage. Alkylating agent mutagenesis is frequently mediated through formation and persistence of a particular DNA base adduct, O6alk...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1985
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424319/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3878366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112215 |
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