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O6 alkylguanine-DNA alkyltransferase activity in human myeloid cells.
The association between alkylating agent exposure and acute nonlymphocytic leukemia in humans indicates that myeloid cells may be particularly susceptible to mutagenic damage. Alkylating agent mutagenesis is frequently mediated through formation and persistence of a particular DNA base adduct, O6alk...
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| Published in: | J Clin Invest |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
1985
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424319/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3878366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112215 |
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