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Insight into the mechanisms and functions of spliceosomal snRNA pseudouridylation

Pseudouridines (Ψs) are the most abundant and highly conserved modified nucleotides found in various stable RNAs of all organisms. Most Ψs are clustered in regions that are functionally important for pre-mRNA splicing. Ψ has an extra hydrogen bond donor that endows RNA molecules with distinct proper...

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Détails bibliographiques
Publié dans:World J Biol Chem
Auteurs principaux: Adachi, Hironori, Yu, Yi-Tao
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Inc 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243145/
https://ncbi.nlm.nih.gov/pubmed/25426264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v5.i4.398
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