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Insight into the mechanisms and functions of spliceosomal snRNA pseudouridylation

Pseudouridines (Ψs) are the most abundant and highly conserved modified nucleotides found in various stable RNAs of all organisms. Most Ψs are clustered in regions that are functionally important for pre-mRNA splicing. Ψ has an extra hydrogen bond donor that endows RNA molecules with distinct proper...

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Detalhes bibliográficos
Publicado no:World J Biol Chem
Main Authors: Adachi, Hironori, Yu, Yi-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243145/
https://ncbi.nlm.nih.gov/pubmed/25426264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v5.i4.398
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