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Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control

In vitro, assembly of box C/D small nucleolar ribonucleoproteins (snoRNPs) involves the sequential recruitment of core proteins to snoRNAs. In vivo, however, assembly factors are required (NUFIP, BCD1, and the HSP90–R2TP complex), and it is unknown whether a similar sequential scheme applies. In thi...

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發表在:J Cell Biol
Main Authors: Bizarro, Jonathan, Charron, Christophe, Boulon, Séverine, Westman, Belinda, Pradet-Balade, Bérengère, Vandermoere, Franck, Chagot, Marie-Eve, Hallais, Marie, Ahmad, Yasmeen, Leonhardt, Heinrich, Lamond, Angus, Manival, Xavier, Branlant, Christiane, Charpentier, Bruno, Verheggen, Céline, Bertrand, Edouard
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242836/
https://ncbi.nlm.nih.gov/pubmed/25404746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404160
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