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Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control

In vitro, assembly of box C/D small nucleolar ribonucleoproteins (snoRNPs) involves the sequential recruitment of core proteins to snoRNAs. In vivo, however, assembly factors are required (NUFIP, BCD1, and the HSP90–R2TP complex), and it is unknown whether a similar sequential scheme applies. In thi...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Bizarro, Jonathan, Charron, Christophe, Boulon, Séverine, Westman, Belinda, Pradet-Balade, Bérengère, Vandermoere, Franck, Chagot, Marie-Eve, Hallais, Marie, Ahmad, Yasmeen, Leonhardt, Heinrich, Lamond, Angus, Manival, Xavier, Branlant, Christiane, Charpentier, Bruno, Verheggen, Céline, Bertrand, Edouard
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242836/
https://ncbi.nlm.nih.gov/pubmed/25404746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404160
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