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Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control

In vitro, assembly of box C/D small nucleolar ribonucleoproteins (snoRNPs) involves the sequential recruitment of core proteins to snoRNAs. In vivo, however, assembly factors are required (NUFIP, BCD1, and the HSP90–R2TP complex), and it is unknown whether a similar sequential scheme applies. In thi...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Autores principales: Bizarro, Jonathan, Charron, Christophe, Boulon, Séverine, Westman, Belinda, Pradet-Balade, Bérengère, Vandermoere, Franck, Chagot, Marie-Eve, Hallais, Marie, Ahmad, Yasmeen, Leonhardt, Heinrich, Lamond, Angus, Manival, Xavier, Branlant, Christiane, Charpentier, Bruno, Verheggen, Céline, Bertrand, Edouard
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242836/
https://ncbi.nlm.nih.gov/pubmed/25404746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404160
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