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MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway

Skin development is governed by complex programs of gene activation and silencing, including microRNA-dependent modulation of gene expression. Here, we show that miR-214 regulates skin morphogenesis and hair follicle (HF) cycling by targeting β-catenin, a key component of the Wnt signaling pathway....

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Ahmed, Mohammed I., Alam, Majid, Emelianov, Vladimir U., Poterlowicz, Krzysztof, Patel, Ankit, Sharov, Andrey A., Mardaryev, Andrei N., Botchkareva, Natalia V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242830/
https://ncbi.nlm.nih.gov/pubmed/25422376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404001
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