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The transmembrane pH gradient drives uphill folate transport in rabbit jejunum. Direct evidence for folate/hydroxyl exchange in brush border membrane vesicles.

In rabbit jejunal, but not ileal brush border membrane vesicles, an outwardly directed OH- gradient (pH 7.7 inside, pH 5.5 outside) markedly stimulated the initial velocity of folate (0.1 microM) uptake compared with uptake in the absence of a pH gradient. Under pH gradient conditions, folate was tr...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Schron, C M, Washington, C, Blitzer, B L
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424271/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4056063/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112205
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