The transmembrane pH gradient drives uphill folate transport in rabbit jejunum. Direct evidence for folate/hydroxyl exchange in brush border membrane vesicles.
In rabbit jejunal, but not ileal brush border membrane vesicles, an outwardly directed OH- gradient (pH 7.7 inside, pH 5.5 outside) markedly stimulated the initial velocity of folate (0.1 microM) uptake compared with uptake in the absence of a pH gradient. Under pH gradient conditions, folate was tr...
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| Pubblicato in: | J Clin Invest |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
1985
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424271/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4056063/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112205 |
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