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A variant of Glanzmann's thrombasthenia with abnormal glycoprotein IIb-IIIa complexes in the platelet membrane.

Patient C.M. presented platelet function defects symptomatic of Glanzmann's thrombasthenia. However, analysis of surface-labeled platelets by SDS-polyacrylamide gel electrophoresis revealed the usual presence of the major glycoproteins, including GP IIb and GP IIIa. Platelet fibrinogen was not detec...

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Udgivet i:J Clin Invest
Principais autores: Nurden, A T, Rosa, J P, Fournier, D, Legrand, C, Didry, D, Parquet, A, Pidard, D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424249/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3818957/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112907
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