Modulation of erythrocyte membrane mechanical stability by 2,3-diphosphoglycerate in the neonatal poikilocytosis/elliptocytosis syndrome.

To explain the transient anemia and poikilocytosis seen during infancy in hereditary elliptocytosis (HE), we resealed erythrocyte (RBC) ghosts from affected children or their elliptocytic parents with 2,3-diphosphoglycerate (DPG) (0-8 mM), a compound that dissociates membrane skeletons, then measure...

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Publicado en:	J Clin Invest
Autores principales:	Mentzer, W C, Iarocci, T A, Mohandas, N, Lane, P A, Smith, B, Lazerson, J, Hays, T
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1987
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424243/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3818955/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112905
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