sn-1,2-Diacylglycerols and phorbol diesters stimulate thromboxane synthesis by de novo synthesis of prostaglandin H synthase in human promyelocytic leukemia cells.

We studied the regulation of thromboxane (TX) synthesis in promyelocytic leukemia cells during macrophage differentiation. Cells treated with 12-O-tetradecanoylphorbol-13-acetate (TPA) showed rates of TXB2 synthesis from exogenous arachidonic acid that exceeded that of control cells by a factor of u...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Goerig, M, Habenicht, A J, Heitz, R, Zeh, W, Katus, H, Kommerell, B, Ziegler, R, Glomset, J A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3102559/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112900
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