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Inactivation of RARβ inhibits Wnt1-induced mammary tumorigenesis by suppressing epithelial-mesenchymal transition

Retinoic acid receptor β (RARβ) has been proposed to act as a tumor suppressor in breast cancer. In contrast, recent data have shown that RARβ promotes ERBB2-induced mammary gland tumorigenesis through remodeling of the stromal compartment and activation of cancer-associated fibroblasts. However, it...

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Publicat a:Nucl Recept Signal
Autors principals: Liu, Xingxing, Giguère, Vincent
Format: Artigo
Idioma:Inglês
Publicat: Nuclear Receptor Signaling Atlas 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242291/
https://ncbi.nlm.nih.gov/pubmed/25422594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1621/nrs.12004
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