NF-κB-induced KIAA1199 promotes survival through EGFR signalling

Constitutive activation of EGFR- and NF-κB-dependent pathways is a hallmark of cancer, yet signalling proteins that connect both oncogenic cascades are poorly characterized. Here we define KIAA1199 as a BCL-3- and p65-dependent gene in transformed keratinocytes. KIAA1199 expression is enhanced on hu...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Shostak, Kateryna, Zhang, Xin, Hubert, Pascale, Göktuna, Serkan Ismail, Jiang, Zheshen, Klevernic, Iva, Hildebrand, Julien, Roncarati, Patrick, Hennuy, Benoit, Ladang, Aurélie, Somja, Joan, Gothot, André, Close, Pierre, Delvenne, Philippe, Chariot, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241993/
https://ncbi.nlm.nih.gov/pubmed/25366117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6232
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