Whole-Genome Scans Provide Evidence of Adaptive Evolution in Malawian Plasmodium falciparum Isolates

BACKGROUND: Selection by host immunity and antimalarial drugs has driven extensive adaptive evolution in Plasmodium falciparum and continues to produce ever-changing landscapes of genetic variation. METHODS: We performed whole-genome sequencing of 69 P. falciparum isolates from Malawi and used popul...

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Опубликовано в: :J Infect Dis
Главные авторы: Ocholla, Harold, Preston, Mark D., Mipando, Mwapatsa, Jensen, Anja T. R., Campino, Susana, MacInnis, Bronwyn, Alcock, Daniel, Terlouw, Anja, Zongo, Issaka, Oudraogo, Jean-Bosco, Djimde, Abdoulaye A., Assefa, Samuel, Doumbo, Ogobara K., Borrmann, Steffen, Nzila, Alexis, Marsh, Kevin, Fairhurst, Rick M., Nosten, Francois, Anderson, Tim J. C., Kwiatkowski, Dominic P., Craig, Alister, Clark, Taane G., Montgomery, Jacqui
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2014
Предметы:
Major Articles and Brief Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241944/
https://ncbi.nlm.nih.gov/pubmed/24948693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu349
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