Whole-Genome Scans Provide Evidence of Adaptive Evolution in Malawian Plasmodium falciparum Isolates

BACKGROUND: Selection by host immunity and antimalarial drugs has driven extensive adaptive evolution in Plasmodium falciparum and continues to produce ever-changing landscapes of genetic variation. METHODS: We performed whole-genome sequencing of 69 P. falciparum isolates from Malawi and used popul...

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Bibliografske podrobnosti
izdano v:J Infect Dis
Main Authors: Ocholla, Harold, Preston, Mark D., Mipando, Mwapatsa, Jensen, Anja T. R., Campino, Susana, MacInnis, Bronwyn, Alcock, Daniel, Terlouw, Anja, Zongo, Issaka, Oudraogo, Jean-Bosco, Djimde, Abdoulaye A., Assefa, Samuel, Doumbo, Ogobara K., Borrmann, Steffen, Nzila, Alexis, Marsh, Kevin, Fairhurst, Rick M., Nosten, Francois, Anderson, Tim J. C., Kwiatkowski, Dominic P., Craig, Alister, Clark, Taane G., Montgomery, Jacqui
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Major Articles and Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241944/
https://ncbi.nlm.nih.gov/pubmed/24948693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu349
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