Whole-Genome Scans Provide Evidence of Adaptive Evolution in Malawian Plasmodium falciparum Isolates

BACKGROUND: Selection by host immunity and antimalarial drugs has driven extensive adaptive evolution in Plasmodium falciparum and continues to produce ever-changing landscapes of genetic variation. METHODS: We performed whole-genome sequencing of 69 P. falciparum isolates from Malawi and used popul...

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Bibliografische gegevens
Gepubliceerd in:J Infect Dis
Hoofdauteurs: Ocholla, Harold, Preston, Mark D., Mipando, Mwapatsa, Jensen, Anja T. R., Campino, Susana, MacInnis, Bronwyn, Alcock, Daniel, Terlouw, Anja, Zongo, Issaka, Oudraogo, Jean-Bosco, Djimde, Abdoulaye A., Assefa, Samuel, Doumbo, Ogobara K., Borrmann, Steffen, Nzila, Alexis, Marsh, Kevin, Fairhurst, Rick M., Nosten, Francois, Anderson, Tim J. C., Kwiatkowski, Dominic P., Craig, Alister, Clark, Taane G., Montgomery, Jacqui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Major Articles and Brief Reports
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241944/
https://ncbi.nlm.nih.gov/pubmed/24948693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu349
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