Molecular basis for the deficiency of complement 1 inhibitor in type I hereditary angioneurotic edema.

Hereditary angioneurotic edema (HANE) results from deficiency of complement 1 inhibitor (C1 INH). In type I HANE, C1 INH is present in serum at levels 5-30% of normals. Using cultured monocytes and biosynthetic labeling of proteins, C1 INH was detected in supernatants of cells from HANE patients at...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Cicardi, M, Igarashi, T, Rosen, F S, Davis, A E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424179/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3818946/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112873
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