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Effect of methotrexate on intracellular folate pools in purified myeloid precursor cells from normal human bone marrow.

We investigated the effects of the antifolate methotrexate on intracellular folate pools of human myeloid precursor cells (MPCs). Immature MPCs, representing 3.2% of the original marrow population, were selected from normal human bone marrow by immune rosetting. The intracellular folate pools were l...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Baram, J, Allegra, C J, Fine, R L, Chabner, B A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424178/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3818945/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112872
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