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Effect of methotrexate on intracellular folate pools in purified myeloid precursor cells from normal human bone marrow.

We investigated the effects of the antifolate methotrexate on intracellular folate pools of human myeloid precursor cells (MPCs). Immature MPCs, representing 3.2% of the original marrow population, were selected from normal human bone marrow by immune rosetting. The intracellular folate pools were l...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Baram, J, Allegra, C J, Fine, R L, Chabner, B A
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1987
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424178/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3818945/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112872
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