Tissue myeloid cells in SIV-infected primates acquire viral DNA through phagocytosis of infected T cells

The viral accessory protein Vpx, expressed by certain simian and human immunodeficiency viruses (SIVs and HIVs), is thought to improve viral infectivity of myeloid cells. We infected 35 Asian macaques and African green monkeys with viruses that do or do not express Vpx, and examined viral targeting...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Calantone, Nina, Wu, Fan, Klase, Zachary, Deleage, Claire, Perkins, Molly, Matsuda, Kenta, Thompson, Elizabeth A., Ortiz, Alexandra M., Vinton, Carol L., Ourmanov, Ilnour, Loré, Karin, Douek, Daniel C., Estes, Jacob D., Hirsch, Vanessa M., Brenchley, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241569/
https://ncbi.nlm.nih.gov/pubmed/25238099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.08.014
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