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Dichloroacetate inhibits glycolysis and augments insulin-stimulated glycogen synthesis in rat muscle.

The decrease in plasma lactate during dichloroacetate (DCA) treatment is attributed to stimulation of lactate oxidation. To determine whether DCA also inhibits lactate production, we measured glucose metabolism in muscles of fed and fasted rats incubated with DCA and insulin. DCA increased glucose-6...

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Detalhes bibliográficos
Main Authors: Clark, A S, Mitch, W E, Goodman, M N, Fagan, J M, Goheer, M A, Curnow, R T
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC424134/
https://ncbi.nlm.nih.gov/pubmed/3543056
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