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Comparison of the Hypoxia PET Tracer (18)F-EF5 to Immunohistochemical Marker EF5 in 3 Different Human Tumor Xenograft Models

The availability of (18)F-labeled and unlabeled 2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)-acetamide (EF5) allows for a comparative assessment of tumor hypoxia by PET and immunohistochemistry; however, the combined use of these 2 approaches has not been fully assessed in vivo. The...

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Dades bibliogràfiques
Publicat a:J Nucl Med
Autors principals: Chitneni, Satish K., Bida, Gerald T., Zalutsky, Michael R., Dewhirst, Mark W.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241176/
https://ncbi.nlm.nih.gov/pubmed/24854792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.114.137448
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