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Crystal structures of designed armadillo repeat proteins: Implications of construct design and crystallization conditions on overall structure

Designed armadillo repeat proteins (dArmRP) are promising modular proteins for the engineering of binding molecules that recognize extended polypeptide chains. We determined the structure of a dArmRP containing five internal repeats and 3rd generation capping repeats in three different states by X-r...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Reichen, Christian, Madhurantakam, Chaithanya, Plückthun, Andreas, Mittl, Peer R E
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241108/
https://ncbi.nlm.nih.gov/pubmed/25132085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2535
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