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Trypsinogen activation as observed in accelerated molecular dynamics simulations
Serine proteases are involved in many fundamental physiological processes, and control of their activity mainly results from the fact that they are synthetized in an inactive form that becomes active upon cleavage. Three decades ago Martin Karplus’s group performed the first molecular dynamics simul...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241106/ https://ncbi.nlm.nih.gov/pubmed/25131668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2532 |
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