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Late, never or non-existent: the inaccessibility of preclinical evidence for new drugs
BACKGROUND AND PURPOSE: Animal studies establish much of the evidence used to support clinical development of new drugs. Recent studies suggest that many preclinical investigations are withheld from publication, leading to exaggerated estimates of clinical utility. We sought to estimate the volume a...
Enregistré dans:
Publié dans: | Br J Pharmacol |
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Auteurs principaux: | , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Blackwell Publishing Ltd
2014
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241091/ https://ncbi.nlm.nih.gov/pubmed/24825131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12771 |
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