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Late, never or non-existent: the inaccessibility of preclinical evidence for new drugs

BACKGROUND AND PURPOSE: Animal studies establish much of the evidence used to support clinical development of new drugs. Recent studies suggest that many preclinical investigations are withheld from publication, leading to exaggerated estimates of clinical utility. We sought to estimate the volume a...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Federico, C A, Carlisle, B, Kimmelman, J, Fergusson, D A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241091/
https://ncbi.nlm.nih.gov/pubmed/24825131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12771
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