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Neurogenin 3–Directed Cre Deletion of Tsc1 Gene Causes Pancreatic Acinar Carcinoma()()

The role of tuberous sclerosis complex (TSC) in the pathogenesis of pancreatic cancers remains largely unknown. The present study shows that neurogenin 3 directed Cre deletion of Tsc1 gene induces the development of pancreatic acinar carcinoma. By cross-breeding the Neurog3-cre mice with Tsc1(loxp/l...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Ding, Li, Han, Lingling, Li, Yin, Zhao, Jing, He, Ping, Zhang, Weizhen
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240920/
https://ncbi.nlm.nih.gov/pubmed/25425965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.08.010
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