E7080 (Lenvatinib), a Multi-Targeted Tyrosine Kinase Inhibitor, Demonstrates Antitumor Activities Against Colorectal Cancer Xenografts

Clinical prognosis of metastasized colorectal carcinoma (CRC) is still not at desired levels and novel drugs are needed. Here, we focused on the multi-tyrosine kinase inhibitor E7080 (Lenvatinib) and assessed its therapeutic efficacy against human CRC cell lines in vitro and human CRC xenografts in...

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Bibliografiska uppgifter
I publikationen:Neoplasia
Huvudupphovsmän: Wiegering, Armin, Korb, Doreen, Thalheimer, Andreas, Kämmerer, Ulrike, Allmanritter, Jan, Matthes, Niels, Linnebacher, Michael, Schlegel, Nicolas, Klein, Ingo, Ergün, Süleyman, Germer, Christoph-Thomas, Otto, Christoph
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240916/
https://ncbi.nlm.nih.gov/pubmed/25425971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.09.008
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