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Post-Stress Block of Kappa Opioid Receptors Rescues Long-Term Potentiation of Inhibitory Synapses and Prevents Reinstatement of Cocaine Seeking

BACKGROUND: Dopaminergic neurons in the ventral tegmental area (VTA) of the brain are an important site of convergence of drugs and stress. We previously identified a form of long-term potentiation of GABAergic synapses on these neurons (LTP(GABA)). Our studies have shown that exposure to acute stre...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Polter, Abigail M., Bishop, Rachel A., Briand, Lisa A., Graziane, Nicholas M., Pierce, R. Christopher, Kauer, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240751/
https://ncbi.nlm.nih.gov/pubmed/24957331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.04.019
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