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Kappa opioid receptors regulate stress-induced cocaine-seeking and synaptic plasticity
Stress facilitates reinstatement of addictive drug-seeking in animals and promotes relapse in humans. Acute stress has marked and long-lasting effects on plasticity at both inhibitory and excitatory synapses on dopamine neurons in the ventral tegmental area (VTA), a key region necessary for drug rei...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632376/ https://ncbi.nlm.nih.gov/pubmed/23473323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.12.034 |
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