Sulforaphane Represses Matrix-Degrading Proteases and Protects Cartilage From Destruction In Vitro and In Vivo

OBJECTIVE: Sulforaphane (SFN) has been reported to regulate signaling pathways relevant to chronic diseases. The aim of this study was to investigate the impact of SFN treatment on signaling pathways in chondrocytes and to determine whether sulforaphane could block cartilage destruction in osteoarth...

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Veröffentlicht in:Arthritis Rheum
Hauptverfasser: Davidson, Rose K, Jupp, Orla, de Ferrars, Rachel, Kay, Colin D, Culley, Kirsty L, Norton, Rosemary, Driscoll, Clare, Vincent, Tonia L, Donell, Simon T, Bao, Yongping, Clark, Ian M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2013
Schlagworte:
Cartilage Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240673/
https://ncbi.nlm.nih.gov/pubmed/23983046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38133
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