Sulforaphane Represses Matrix-Degrading Proteases and Protects Cartilage From Destruction In Vitro and In Vivo

OBJECTIVE: Sulforaphane (SFN) has been reported to regulate signaling pathways relevant to chronic diseases. The aim of this study was to investigate the impact of SFN treatment on signaling pathways in chondrocytes and to determine whether sulforaphane could block cartilage destruction in osteoarth...

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Vydáno v:Arthritis Rheum
Hlavní autoři: Davidson, Rose K, Jupp, Orla, de Ferrars, Rachel, Kay, Colin D, Culley, Kirsty L, Norton, Rosemary, Driscoll, Clare, Vincent, Tonia L, Donell, Simon T, Bao, Yongping, Clark, Ian M
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2013
Témata:
Cartilage Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240673/
https://ncbi.nlm.nih.gov/pubmed/23983046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38133
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