Sulforaphane Represses Matrix-Degrading Proteases and Protects Cartilage From Destruction In Vitro and In Vivo

OBJECTIVE: Sulforaphane (SFN) has been reported to regulate signaling pathways relevant to chronic diseases. The aim of this study was to investigate the impact of SFN treatment on signaling pathways in chondrocytes and to determine whether sulforaphane could block cartilage destruction in osteoarth...

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Detalhes bibliográficos
Publicado no:Arthritis Rheum
Main Authors: Davidson, Rose K, Jupp, Orla, de Ferrars, Rachel, Kay, Colin D, Culley, Kirsty L, Norton, Rosemary, Driscoll, Clare, Vincent, Tonia L, Donell, Simon T, Bao, Yongping, Clark, Ian M
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2013
Assuntos:
Cartilage Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240673/
https://ncbi.nlm.nih.gov/pubmed/23983046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38133
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