Genistein potentiates the antitumor effect of 5-fluorouracil by inducing apoptosis and autophagy in human pancreatic cancer cells

BACKGROUND: Although 5-fluorouracil (5-FU)-based combination chemotherapy (i.e. FOLFIRINOX) has demonstrated effectiveness against pancreatic cancer, novel therapeutic strategies must be developed to increase the therapeutic window of these cytotoxic agents. Genistein is a soy-derived isoflavone wit...

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Detaylı Bibliyografya
Yayımlandı:Anticancer Res
Asıl Yazarlar: Suzuki, Rei, Kang, Ya'an, Li, Xinqun, Roife, David, Zhang, Ran, Fleming, Jason B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240628/
https://ncbi.nlm.nih.gov/pubmed/25202045
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