Molecular mechanisms of McArdle's disease (muscle glycogen phosphorylase deficiency). RNA and DNA analysis.

Lack of muscle glycogen phosphorylase activity leads to McArdle's disease, a rare metabolic myopathy. To investigate its molecular basis at the nucleic acid level, we isolated muscle phosphorylase cDNA clones from a human cDNA library in Escherichia coli plasmid pBR 322. Subcloning of one inser...

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Bibliografiske detaljer
Main Authors: Gautron, S, Daegelen, D, Mennecier, F, Dubocq, D, Kahn, A, Dreyfus, J C
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC424040/
https://ncbi.nlm.nih.gov/pubmed/3466902
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