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Molecular mechanisms of McArdle's disease (muscle glycogen phosphorylase deficiency). RNA and DNA analysis.

Lack of muscle glycogen phosphorylase activity leads to McArdle's disease, a rare metabolic myopathy. To investigate its molecular basis at the nucleic acid level, we isolated muscle phosphorylase cDNA clones from a human cDNA library in Escherichia coli plasmid pBR 322. Subcloning of one insertion...

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Publicado no:J Clin Invest
Principais autores: Gautron, S, Daegelen, D, Mennecier, F, Dubocq, D, Kahn, A, Dreyfus, J C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424040/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3466902/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112794
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