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Molecular mechanisms of epithelial–mesenchymal transition

The transdifferentiation of epithelial cells into motile mesenchymal cells, a process known as epithelial–mesenchymal transition (EMT), is integral in development, wound healing and stem cell behaviour, and contributes pathologically to fibrosis and cancer progression. This switch in cell differenti...

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Détails bibliographiques
Publié dans:Nat Rev Mol Cell Biol
Auteurs principaux: Lamouille, Samy, Xu, Jian, Derynck, Rik
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240281/
https://ncbi.nlm.nih.gov/pubmed/24556840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3758
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