SUCLG2 identified as both a determinator of CSF Aβ(1–42) levels and an attenuator of cognitive decline in Alzheimer's disease

Cerebrospinal fluid amyloid-beta 1–42 (Aβ(1–42)) and phosphorylated Tau at position 181 (pTau(181)) are biomarkers of Alzheimer's disease (AD). We performed an analysis and meta-analysis of genome-wide association study data on Aβ(1–42) and pTau(181) in AD dementia patients followed by independ...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Ramirez, Alfredo, van der Flier, Wiesje M., Herold, Christine, Ramonet, David, Heilmann, Stefanie, Lewczuk, Piotr, Popp, Julius, Lacour, André, Drichel, Dmitriy, Louwersheimer, Eva, Kummer, Markus P., Cruchaga, Carlos, Hoffmann, Per, Teunissen, Charlotte, Holstege, Henne, Kornhuber, Johannes, Peters, Oliver, Naj, Adam C., Chouraki, Vincent, Bellenguez, Céline, Gerrish, Amy, Heun, Reiner, Frölich, Lutz, Hüll, Michael, Buscemi, Lara, Herms, Stefan, Kölsch, Heike, Scheltens, Philip, Breteler, Monique M., Rüther, Eckart, Wiltfang, Jens, Goate, Alison, Jessen, Frank, Maier, Wolfgang, Heneka, Michael T., Becker, Tim, Nöthen, Markus M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240204/
https://ncbi.nlm.nih.gov/pubmed/25027320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu372
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