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Human Immunodeficiency Virus Type-1 Protein Tat Induces Tumor Necrosis Factor-α-Mediated Neurotoxicity

HIV-1 infection causes, with increasing prevalence, neurological disorders characterized in part by neuronal cell death. The HIV-1 protein Tat has been shown to be directly and indirectly neurotoxic. Here, we tested the hypothesis that a non-neurotoxic epitope of Tat can, through actions on immune c...

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Detalhes bibliográficos
Main Authors: Buscemi, Lara, Ramonet, David, Geiger, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080622/
https://ncbi.nlm.nih.gov/pubmed/17451964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.03.004
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