Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes

AIMS: During activation of cardiac myocytes, less than 1% of cytosolic Ca is free; the rest is bound to buffers, largely SERCA, and troponin C. Signalling by phosphorylation, as occurs during β-adrenergic stimulation, changes the Ca-binding affinity of these proteins and may affect the systolic Ca t...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cardiovasc Res
Hlavní autoři: Briston, Sarah J., Dibb, Katharine M., Solaro, R. John, Eisner, David A., Trafford, Andrew W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240166/
https://ncbi.nlm.nih.gov/pubmed/25183792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu201
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky