Compensatory increase in alpha 1-globin gene expression in individuals heterozygous for the alpha-thalassemia-2 deletion.

alpha-Globin is encoded by the two adjacent genes, alpha 1 and alpha 2. Although it is clearly established that both alpha-globin genes are expressed, their relative contributions to alpha-globin messenger RNA (mRNA) and protein synthesis are not fully defined. Furthermore, changes that may occur in...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Liebhaber, S A, Cash, F E, Main, D M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423986/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4044827/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112058
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