Residue Leu(940) Has a Crucial Role in the Linkage and Reaction Specificity of the Glucansucrase GTF180 of the Probiotic Bacterium Lactobacillus reuteri 180

Highly conserved glycoside hydrolase family 70 glucansucrases are able to catalyze the synthesis of α-glucans with different structure from sucrose. The structural determinants of glucansucrase specificity have remained unclear. Residue Leu(940) in domain B of GTF180, the glucansucrase of the probio...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Meng, Xiangfeng, Dobruchowska, Justyna M., Pijning, Tjaard, López, Cesar A., Kamerling, Johannis P., Dijkhuizen, Lubbert
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239627/
https://ncbi.nlm.nih.gov/pubmed/25288798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602524
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