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Identification of a new class of inducible receptors on platelets. Thrombospondin interacts with platelets via a GPIIb-IIIa-independent mechanism.

Thrombospondin with fibrinogen, fibronectin, and von Willebrand factor binds to platelets stimulated with agonists and support platelet adhesive functions. The receptors for the latter three proteins are associated with membrane glycoprotein GPIIb-IIIa. Thrombasthenic platelets deficient in GPIIb-II...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Aiken, M L, Ginsberg, M H, Plow, E F
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423947/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3782477/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112767
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