Identification of a new class of inducible receptors on platelets. Thrombospondin interacts with platelets via a GPIIb-IIIa-independent mechanism.

Thrombospondin with fibrinogen, fibronectin, and von Willebrand factor binds to platelets stimulated with agonists and support platelet adhesive functions. The receptors for the latter three proteins are associated with membrane glycoprotein GPIIb-IIIa. Thrombasthenic platelets deficient in GPIIb-II...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Aiken, M L, Ginsberg, M H, Plow, E F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423947/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3782477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112767
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