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Treatment with aldose reductase inhibitor or with myo-inositol arrests deterioration of the electroretinogram of diabetic rats.

Biochemical abnormalities in the retinal pigment epithelium of experimentally diabetic animals include increased sorbitol and decreased myo-inositol. Diabetes also causes a progressive reduction in the amplitude of the c-wave of the electroretinogram of the pigmented rat. The c-wave is generated by...

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Autores principales: MacGregor, L C, Matschinsky, F M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1985
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC423926/
https://ncbi.nlm.nih.gov/pubmed/3928685
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