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Treatment with aldose reductase inhibitor or with myo-inositol arrests deterioration of the electroretinogram of diabetic rats.

Biochemical abnormalities in the retinal pigment epithelium of experimentally diabetic animals include increased sorbitol and decreased myo-inositol. Diabetes also causes a progressive reduction in the amplitude of the c-wave of the electroretinogram of the pigmented rat. The c-wave is generated by...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: MacGregor, L C, Matschinsky, F M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1985
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423926/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3928685/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112048
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