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Osteoprotegerin deficiency limits angiotensin II-induced aortic dilatation and rupture in the apolipoprotein E-knockout mouse

OBJECTIVE: Mounting evidence links osteoprotegerin (OPG) with cardiovascular disease. Elevated serum and aortic tissue OPG are associated with the presence and growth of abdominal aortic aneurysm (AAA) in humans, however, a role for OPG in AAA pathogenesis remains to be shown. We examined the functi...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Moran, Corey S., Jose, Roby J., Biros, Erik, Golledge, Jonathan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239170/
https://ncbi.nlm.nih.gov/pubmed/25301844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304587
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