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Osteoprotegerin deficiency limits angiotensin II-induced aortic dilatation and rupture in the apolipoprotein E-knockout mouse
OBJECTIVE: Mounting evidence links osteoprotegerin (OPG) with cardiovascular disease. Elevated serum and aortic tissue OPG are associated with the presence and growth of abdominal aortic aneurysm (AAA) in humans, however, a role for OPG in AAA pathogenesis remains to be shown. We examined the functi...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4239170/ https://ncbi.nlm.nih.gov/pubmed/25301844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304587 |
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