Dramatic response to dabrafenib and trametinib combination in a BRAF V600E-mutated cholangiocarcinoma: implementation of a molecular tumour board and next-generation sequencing for personalized medicine

This is the case of a 47-year-old woman diagnosed with chemotherapy and radiation-refractory BRAF V600E mutant, poorly differentiated intrahepatic cholangiocarcinoma (ICC), with multiple metastatic lesions within the liver, lungs, pleura, and bone, stage IV. Discussion of her malignancy’s next-gener...

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Detalhes bibliográficos
Publicado no:Ecancermedicalscience
Main Authors: Loaiza-Bonilla, Arturo, Clayton, Erica, Furth, Emma, O’Hara, Mark, Morrissette, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: Cancer Intelligence 2014
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239128/
https://ncbi.nlm.nih.gov/pubmed/25435907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2014.479
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